Phylogenetic Analysis of Lednice Orthobunyavirus
نویسندگان
چکیده
منابع مشابه
Phylogenetic analysis of Bunyamwera and Ngari viruses (family Bunyaviridae, genus Orthobunyavirus) isolated in Kenya.
Orthobunyaviruses, tri-segmented, negative-sense RNA viruses, have long been associated with mild to severe human disease in Africa, but not haemorrhagic fever. However, during a Rift Valley fever outbreak in East Africa in 1997-1998, Ngari virus was isolated from two patients and antibody detected in several others with haemorrhagic fever. The isolates were used to identify Ngari virus as a na...
متن کاملGenomic and phylogenetic characterization of Leanyer virus, a novel orthobunyavirus isolated in northern Australia.
Leanyer virus (LEAV), currently classified as a member of the genus Orthobunyavirus, in the family Bunyaviridae, was originally isolated from a pool of Anopheles meraukensis mosquitoes, collected at Leanyer, Northern Territory, Australia in 1974. When it failed to react in serological tests with antisera from other known viruses, full-length genomic sequencing was pursued to determine the relat...
متن کاملEtymologia: Orthobunyavirus
21. Grimstad PR, Shabino CL, Calisher CH, Waldman RJ. A case of encephalitis in a human associated with a serologic rise to Jamestown Canyon virus. Am J Trop Med Hyg. 1982; 31:1238–44. 22. Centers for Disease Control and Prevention. Human Jamestown Canyon virus infection—Montana, 2009. MMWR Morb Mortal Wkly Rep. 2011;60:652–5. 23. Artsob H. Arbovirus activity in Canada. Arch Virol. 1990; Suppl:...
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The virion glycoproteins Gn and Gc of Bunyamwera orthobunyavirus (family Bunyaviridae) are encoded by the M RNA genome segment and have roles in both viral attachment and membrane fusion. To investigate further the structure and function of the Gc protein in viral replication, we generated 12 mutants that contain truncations from the N terminus. The effects of these deletions were analysed with...
متن کاملMutational analysis of the Bunyamwera orthobunyavirus nucleocapsid protein gene.
The bunyavirus nucleocapsid protein, N, is a multifunctional protein that encapsidates each of the three negative-sense genome segments to form ribonucleoprotein complexes that are the functional templates for viral transcription and replication. In addition, N protein molecules interact with themselves to form oligomers, with the viral L (RNA polymerase) protein, with the carboxy-terminal regi...
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ژورنال
عنوان ژورنال: Microorganisms
سال: 2019
ISSN: 2076-2607
DOI: 10.3390/microorganisms7100447